EPH Receptor B1 antibody (AA 955-984)

Catalog No. ABIN7877230

The Rabbit Polyclonal anti-EPH Receptor B1 antibody (ABIN7877230) specifically detects EPH Receptor B1 in WB and IHC (p). The antibody is reactive with Human and Mouse samples.

Quick Overview for EPH Receptor B1 antibody (AA 955-984) (ABIN7877230)

Target: EPH Receptor B1 (EPHB1)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-EPH Receptor B1 Antibody

Binding Specificity: AA 955-984

Purpose: Eph Receptor B1 Antibody / EphB1

Purification: SAS precipitation

Immunogen: A portion of amino acids 955-984 from the human protein was used as the immunogen for the Eph Receptor B1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Eph Receptor B1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the EphB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for EPH Receptor B1

Target: EPH Receptor B1 (EPHB1)

Alternative Name: Eph Receptor B1

Background: Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

UniProt: P54762

Pathways: RTK Signaling