UNG antibody (AA 96-313)

Catalog No. ABIN7877249

This Rabbit Polyclonal antibody specifically detects UNG in WB, ELISA, IF, IHC (p) and FACS. It exhibits reactivity toward Human, Mouse, Rat and Monkey.

Quick Overview for UNG antibody (AA 96-313) (ABIN7877249)

Target: UNG (Uracil-DNA Glycosylase (UNG))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UNG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-UNG Antibody

Binding Specificity: AA 96-313

Purpose: UNG Antibody / Uracil-DNA Glycosylase

Purification: Affinity purified

Immunogen: Recombinant human protein (amino acids E96-L313) was used as the immunogen for the UNG antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the UNG antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the UNG antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for UNG

Target: UNG (Uracil-DNA Glycosylase (UNG))

Alternative Name: UNG

Background: Uracil-DNA glycosylase, also known as UNG or UDG, is a human gene though orthologs exist ubiquitously among prokaryotes and eukaryotes and even in some DNA viruses. The first uracil DNA-glycosylase was isolated from Escherichia coli. This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene, which has been confused with this gene, in the literature and some databases.

UniProt: P13051

Pathways: DNA Damage Repair, Production of Molecular Mediator of Immune Response