PSPC1 antibody (AA 96-489)

Catalog No. ABIN7877253

The Rabbit Polyclonal anti-PSPC1 antibody is suitable to detect PSPC1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IF, IHC (p) and FACS.

Quick Overview for PSPC1 antibody (AA 96-489) (ABIN7877253)

Target: PSPC1 (Paraspeckle Component 1 (PSPC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSPC1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Product Details anti-PSPC1 Antibody

Binding Specificity: AA 96-489

Purpose: Paraspeckle component 1 Antibody / PSPC1

Purification: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (E96-Q489) was used as the immunogen for the Paraspeckle component 1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Paraspeckle component 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the Paraspeckle component 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for PSPC1

Target: PSPC1 (Paraspeckle Component 1 (PSPC1))

Alternative Name: Paraspeckle component 1

Background: This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified.

UniProt: Q8WXF1