Recombinant UBA3 antibody (Catalytic Subunit)

Catalog No. ABIN7877514

The Rabbit Monoclonal anti-UBA3 antibody is suitable to detect UBA3 in samples from Human. It has been validated for WB.

Quick Overview for Recombinant UBA3 antibody (Catalytic Subunit) (ABIN7877514)

Target: UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This UBA3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 28U91

Product Details anti-UBA3 Antibody

Binding Specificity: Catalytic Subunit

Purpose: UBA3 Antibody / Ubiquitin-activating enzyme 3 / UBE1C

Purification: Affinity chromatography

Immunogen: A synthetic peptide from human NEDD8-activating enzyme E1 catalytic subunit protein was used as the immunogen for the UBA3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the UBA3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the UBA3 antibody at -20oC.

Target Details for UBA3

Target: UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

Alternative Name: UBA3

Background: NEDD8-activating enzyme E1 catalytic subunit (UBA3) is the catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression. [UniProt]

UniProt: Q8TBC4