Annexin A2 antibody (full length)

Catalog No. ABIN7877682

The Mouse Monoclonal anti-Annexin A2 antibody is suitable to detect Annexin A2 in samples from Human. It has been validated for IHC (p).

Quick Overview for Annexin A2 antibody (full length) (ABIN7877682)

Target: Annexin A2 (ANXA2)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Annexin A2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: 3D5-4

Product Details anti-Annexin A2 Antibody

Binding Specificity: full length

Purpose: ANXA2 Antibody / Annexin A2

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the ANXA2 antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the ANXA2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ANXA2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Annexin A2

Target: Annexin A2 (ANXA2)

Alternative Name: ANXA2

Background: The Annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain which binds phospholipids in a Ca2+-dependent manner and a unique amino-terminal region which may confer binding specificity. The interaction between these proteins and biological membranes has led to the hypothesis that they are involved in cellular trafficking processes such as endocytosis, exocytosis and cellular adhesion. Annexin I, alternatively referred to as lipocortin, has been implicated as a mediator of the anti-inflammatory response produced by glucocorticoids and as an inhibitor of cPLA2, a potent mediator of inflammation. Annexin II, also called p36, exists as a monomer or as a heterotetramer, complexed with the S-100-related protein p11. This complex is termed Calpactin I. In the tetrameric form, Annexin II is an efficient substrate of PKC family and Src pp60.

UniProt: P07355

Pathways: S100 Proteins