CNOT10 antibody (full length)

Catalog No. ABIN7877840

This Mouse Monoclonal antibody specifically detects CNOT10 in WB, ELISA, IF and FACS. It exhibits reactivity toward Human.

Quick Overview for CNOT10 antibody (full length) (ABIN7877840)

Target: CNOT10 (CCR4-NOT Transcription Complex, Subunit 10 (CNOT10))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CNOT10 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Grade: Carrier-free

Clone: PCRP-CNOT10-1D5

Product Details anti-CNOT10 Antibody

Binding Specificity: full length

Purpose: CNOT10 Antibody / CCR4-NOT transcription complex subunit 10 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the CNOT10 antibody.

Isotype: IgG2c

Application Details

Application Notes: Optimal dilution of the CNOT10 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the CNOT10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CNOT10

Target: CNOT10 (CCR4-NOT Transcription Complex, Subunit 10 (CNOT10))

Alternative Name: CNOT10

Background: CNOT10 is a subunit of the CCR4-NOT complex which consists of at least five other CNOT subunit proteins and TAB182. The CCR4-NOT complex is an evolutionarily conserved, multi-component complex known to be involved in transcription, as well as in mRNA degradation. Various subunits (e.g. CNOT1, CNOT3) are uniquely involved in influencing nuclear hormone receptor activities. In effect, this complex has an important role as a transcription regulator and repressor of nuclear receptor signaling that is relevant to the molecular pathways involved in cancer. The CCR4-NOT complex is also involved in the regulation of Histone H3 lysine 4 methylation through a ubiquitin-dependent pathway that likely involves the proteasome.

UniProt: Q9H9A5