GTF2H2C antibody (full length)

Catalog No. ABIN7878283

The Mouse Monoclonal anti-GTF2H2C antibody (Clone PCRP-GTF2H2C-2C9) (ABIN7878283) specifically detects GTF2H2C in WB, IF, IHC (p) and FACS. The antibody is reactive with Human samples.

Quick Overview for GTF2H2C antibody (full length) (ABIN7878283)

Target: GTF2H2C (General Transcription Factor IIH, Polypeptide 2C (GTF2H2C))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GTF2H2C antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: PCRP-GTF2H2C-2C9

Product Details anti-GTF2H2C Antibody

Binding Specificity: full length

Purpose: GTF2H2C Antibody

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human GTF2H2C protein was used as the immunogen for the GTF2H2C antibody.

Isotype: IgG2c

Application Details

Application Notes: Optimal dilution of the GTF2H2C antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot the GTF2H2C antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for GTF2H2C

Target: GTF2H2C (General Transcription Factor IIH, Polypeptide 2C (GTF2H2C))

Alternative Name: GTF2H2C

Background: Initiation of transcription from protein-coding genes in eukaryotes is a complex process that requires RNA polymerase II, as well as families of basal transcription factors. Binding of the factor TFIID (TBP) to the TATA box is believed to be the first step in the formation of a multiprotein complex containing several additional factors, including TFIIA, TFIIB, TFIIE, TFIIF and TFIIH. TFIIH (or BTF2) is a multisubunit transcription/DNA repair factor that possesses several enzymatic activities. The core of TFIIH is composed of five subunits, designated p89 (XPB or ERCC3), p62, p52, p44 and p34. Additional subunits of the TFIIH complex are p80 (XPD or ERCC2) and the ternary kinase complex composed of Cdk7, cyclin H and MAT1. Both p89 and p80 have ATP-dependent helicase activity. The p62, p52 and p44 subunits have been shown to be involved in nucleotide excision repair.

UniProt: Q6P1K8