JunB antibody (full length)

Catalog No. ABIN7878464

This Mouse Monoclonal antibody specifically detects JunB in IF and FACS. It exhibits reactivity toward Human.

Quick Overview for JunB antibody (full length) (ABIN7878464)

Target: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This JunB antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Grade: Carrier-free

Clone: PCRP-JUNB-3G2

Product Details anti-JunB Antibody

Binding Specificity: full length

Purpose: JUNB Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human JUNB protein was used as the immunogen for the JUNB antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the JUNB antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the JUNB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for JunB

Target: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Alternative Name: JUNB

Background: The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes, Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.

UniProt: P17275