JunB antibody (full length)

Catalog No. ABIN7878466

The Mouse Monoclonal anti-JunB antibody (Clone PCRP-JUNB-3G11) (ABIN7878466) specifically detects JunB in IF and FACS. The antibody is reactive with Human samples.

Quick Overview for JunB antibody (full length) (ABIN7878466)

Target: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This JunB antibody is un-conjugated

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Grade: Carrier-free

Clone: PCRP-JUNB-3G11

Product Details anti-JunB Antibody

Binding Specificity: full length

Purpose: JUNB Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human JUNB protein was used as the immunogen for the JUNB antibody.

Isotype: IgG2c

Application Details

Application Notes: Optimal dilution of the JUNB antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the JUNB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for JunB

Target: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Alternative Name: JUNB

Background: The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein, along with c-Fos, is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes, Jun B and Jun D, have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family.

UniProt: P17275