Recombinant KRT6A antibody (full length)

Catalog No. ABIN7878502

The Mouse Monoclonal anti-KRT6A antibody (Clone rKRT6A-2100) (ABIN7878502) specifically detects KRT6A in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant KRT6A antibody (full length) (ABIN7878502)

Target: KRT6A (Keratin 6A (KRT6A))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT6A antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: RKRT6A-2100

Product Details anti-KRT6A Antibody

Binding Specificity: full length

Purpose: Recombinant Cytokeratin 6A Antibody (azide and preservative free)

Purification: Protein G affinity chromatography

Immunogen: A recombinant full-length human Cytokeratin 6A protein was used as the immunogen for this recombinant Cytokeratin 6A antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Cytokeratin 6A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Cytokeratin 6A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for KRT6A

Target: KRT6A (Keratin 6A (KRT6A))

Alternative Name: Cytokeratin 6A

Background: This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas.

UniProt: P02538