Recombinant KRT6A antibody (full length)

Catalog No. ABIN7878503

This Mouse Monoclonal antibody specifically detects KRT6A in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant KRT6A antibody (full length) (ABIN7878503)

Target: KRT6A (Keratin 6A (KRT6A))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KRT6A antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RKRT6A-2100

Product Details anti-KRT6A Antibody

Binding Specificity: full length

Purpose: Recombinant Cytokeratin 6A Antibody

Purification: Protein G affinity chromatography

Immunogen: A recombinant full-length human Cytokeratin 6A protein was used as the immunogen for this recombinant Cytokeratin 6A antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Cytokeratin 6A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant Cytokeratin 6A antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for KRT6A

Target: KRT6A (Keratin 6A (KRT6A))

Alternative Name: Cytokeratin 6A

Background: This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75 % of head and neck squamous cell carcinomas.

UniProt: P02538