Recombinant Cytokeratin 7 antibody (full length)

Catalog No. ABIN7878509

This Mouse Monoclonal antibody specifically detects Cytokeratin 7 in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant Cytokeratin 7 antibody (full length) (ABIN7878509)

Target: Cytokeratin 7 (KRT7) (Keratin 7 (KRT7))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cytokeratin 7 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RKRT7-8763

Product Details anti-Cytokeratin 7 Antibody

Binding Specificity: full length

Purpose: Recombinant KRT7 Antibody / Cytokeratin 7

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human KRT7 protein was used as the immunogen for the recombinant KRT7 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the recombinant KRT7 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the recombinant KRT7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Cytokeratin 7

Target: Cytokeratin 7 (KRT7) (Keratin 7 (KRT7))

Alternative Name: KRT7

Background: It recognizes an intermediate filament protein (IFP) of 55 kDa, which is identified as cytokeratin 7. This mAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract.This mAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).

UniProt: P08729