MED22 antibody (full length)

Catalog No. ABIN7878592

The Mouse Monoclonal anti-MED22 antibody (Clone PCRP-MED22-2A7) (ABIN7878592) specifically detects MED22 in ELISA, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for MED22 antibody (full length) (ABIN7878592)

Target: MED22 (Mediator Complex Subunit 22 (MED22))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MED22 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Grade: Carrier-free

Clone: PCRP-MED22-2A7

Product Details anti-MED22 Antibody

Binding Specificity: full length

Purpose: MED22 Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the MED22 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the MED22 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the MED22 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for MED22

Target: MED22 (Mediator Complex Subunit 22 (MED22))

Alternative Name: MED22

Background: Med22 is a subunit of the RNA polymerase II (Pol II) transcriptional mediator complex. The mediator complex is a coactivator involved in the regulated transcription of Pol II-dependent genes. Functioning as a bridge to convey information from gene-specific regulatory proteins to the basal Pol II transcription machinery, the mediator complex is recruited to promoter regions by directly interacting with regulatory proteins. The mediator complex also serves as a scaffold for the assembly of a functional pre-initiation complex with Pol II and other general transcription factors. Med22 (mediator complex subunit 22), also known as SURF5 (surfeit locus protein 5), is a ubiquitously expressed 200 amino acid nuclear protein that is one of several components of the mediator complex. There are two isoforms of Med22 that are produced as a result of alternative splicing events.

UniProt: Q15528

Pathways: Regulation of Lipid Metabolism by PPARalpha