PBX2 antibody (full length)

Catalog No. ABIN7878837

The Mouse Monoclonal anti-PBX2 antibody is suitable to detect PBX2 in samples from Human. It has been validated for ELISA, IF and FACS.

Quick Overview for PBX2 antibody (full length) (ABIN7878837)

Target: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PBX2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Grade: Carrier-free

Clone: PCRP-PBX2-1C4

Product Details anti-PBX2 Antibody

Binding Specificity: full length

Purpose: PBX2 Antibody (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human PBX2 protein was used as the immunogen for the PBX2 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the PBX2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the PBX2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PBX2

Target: PBX2 (Pre-B-Cell Leukemia Homeobox Protein 2 (PBX2))

Alternative Name: PBX2

Background: Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1,19)(q23,p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92 % and 94 % respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.

UniProt: P40425

Pathways: Skeletal Muscle Fiber Development