RPA2 antibody (full length)
Quick Overview for RPA2 antibody (full length) (ABIN7878907)
Target
See all RPA2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- full length
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Purpose
- RPA32 Antibody / RPA2 / Replication Protein A2
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Purification
- Protein A/G affinity
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Immunogen
- Recombinant human full-length Replication Protein A2 protein was used as the immunogen for the RPA32 antibody.
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Isotype
- IgG1, kappa
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Application Notes
- Optimal dilution of the RPA32 antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the RPA32 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- RPA2 (Replication Protein A2, 32kDa (RPA2))
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Alternative Name
- RPA32
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Background
- Recognizes a protein of 34 kDa, identified as a subunit of Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB). RPA from human cells is a stable heterotrimer of 70 kDa, 32-34 kDa, and 11-14 kDa subunits (RPA70, RPA32, and RPA14 respectively). It is involved in DNA replication, repair, and recombination. RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase (pol) alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation.
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UniProt
- P15927
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Pathways
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
Target
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