The Rabbit Monoclonal anti-RPA2 antibody (Clone RPA2-3140R) (ABIN7878910) specifically detects RPA2 in WB.
The antibody is reactive with Human samples.
Optimal dilution of the recombinant RPA32 antibody should be determined by the researcher.
Restrictions
For Research Use only
Format
Liquid
Concentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Preservative
Azide free
Storage
4 °C,-20 °C
Storage Comment
Store the recombinant RPA32 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Target
RPA2
(Replication Protein A2, 32kDa (RPA2))
Alternative Name
RPA32
Background
Recognizes a protein of 34 kDa, identified as a subunit of Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB). RPA from human cells is a stable heterotrimer of 70 kDa, 32-34 kDa, and 11-14 kDa subunits (RPA70, RPA32, and RPA14 respectively). It is involved in DNA replication, repair, and recombination. RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase (pol) alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation.