Osteopontin antibody (full length)

Catalog No. ABIN7878985

The Rat Monoclonal anti-Osteopontin antibody (Clone OSP-4589) (ABIN7878985) specifically detects Osteopontin in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Osteopontin antibody (full length) (ABIN7878985)

Target: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This Osteopontin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: OSP-4589

Product Details anti-Osteopontin Antibody

Binding Specificity: full length

Purpose: Osteopontin Antibody / OPN / SPP1

Purification: Protein A/G affinity

Immunogen: Recombinant full-length rat Spp1/Osteopontin protein was used as the immunogen for the Osteopontin antibody.

Isotype: IgG1

Application Details

Application Notes: Optimal dilution of the Osteopontin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Osteopontin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Osteopontin

Target: Osteopontin (SPP1) (Secreted phosphoprotein 1 (SPP1))

Alternative Name: Osteopontin

Background: Osteopontin is a bone matrix protein and a cytokine secreted by activated T cells. Osteopontin (OPN, also designated bone sialoprotein 1, urinary stone protein, spp-1, -1, nephropontin, uropontin) is an extracellular matrix cell adhesion phosphoglycoprotein. OPN is deposited into unmineralized matrix prior to calcification leading to localization at various tissue interfaces including cement lines, lamina limitans, and between collagen fibrils of fully matured hard tissues. While OPN is a major product of osteoblasts, it is also synthesized by brain and kidney cells. OPNs isolated from or secreted by various tissues have molecular weights due to post-translational modifications. OPN functions as a substrate for transglutaminase and is involved in cell adhesion, chemoattraction and immunomodulation.

UniProt: P10451

Pathways: Regulation of Cell Size