Recombinant SELPLG antibody (full length)

Catalog No. ABIN7879001

This Rabbit Monoclonal antibody specifically detects SELPLG in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant SELPLG antibody (full length) (ABIN7879001)

Target: SELPLG (Selectin P Ligand (SELPLG))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SELPLG antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: PSGL1-8192R

Product Details anti-SELPLG Antibody

Binding Specificity: full length

Purpose: PSGL-1 Antibody / CD162

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the PSGL-1 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the PSGL-1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PSGL-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for SELPLG

Target: SELPLG (Selectin P Ligand (SELPLG))

Alternative Name: PSGL-1

Background: CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.

UniProt: Q14242