Recombinant Thrombomodulin antibody (full length)

Catalog No. ABIN7879142

This Rabbit Monoclonal antibody specifically detects Thrombomodulin in IHC (p). It exhibits reactivity toward Human.

Quick Overview for Recombinant Thrombomodulin antibody (full length) (ABIN7879142)

Target: Thrombomodulin (THBD)

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Thrombomodulin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: THBD-8188R

Product Details anti-Thrombomodulin Antibody

Binding Specificity: full length

Purpose: CD141 Antibody / Thrombomodulin

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human protein was used as the immunogen for the CD141 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the CD141 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CD141 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Thrombomodulin

Target: Thrombomodulin (THBD)

Alternative Name: CD141

Background: It recognizes a protein of 75 kDa, identified as Thrombomodulin, or CD141. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi s sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.

UniProt: P07204