TTR antibody (full length)

Catalog No. ABIN7879206

The Mouse Monoclonal anti-TTR antibody is suitable to detect TTR in samples from Human. It has been validated for WB and IHC (p).

Quick Overview for TTR antibody (full length) (ABIN7879206)

Target: TTR (Transthyretin (TTR))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TTR antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TTR-4292

Product Details anti-TTR Antibody

Binding Specificity: full length

Purpose: Transthyretin Antibody / TTR / Prealbumin

Purification: Protein G affinity chromatography

Immunogen: Recombinant human full-length protein was used as the immunogen for the Transthyretin antibody.

Isotype: IgG2c, kappa

Application Details

Application Notes: Optimal dilution of the Transthyretin antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Transthyretin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for TTR

Target: TTR (Transthyretin (TTR))

Alternative Name: Transthyretin

Background: Prealbumin, also designated transthyretin, is a major thyroid-hormone binding protein involved in transporting thyroxine from the bloodstream to the brain. Prealbumin is located in the cytoplasm and in the vesicles of developing rat brain cells, and is thought to be transported there from the cerebrospinal fluid via endocytosis. Sequence variants of this protein have been identified in amyloid fibrils from patients with familial amyloidotic polyneuropathy (FAP), the most common form of hereditary systemic amyloidosis. Although the biologically active form of Prealbumin is a tetramer, the amyloidogenic intermediate is thought to be a monomeric species. Prealbumin also binds to the retinol carrier protein RBP (retinol-binding protein).

UniProt: P02766

Pathways: Hormone Transport