Tyrosinase-Related Protein 1 antibody (full length)

Catalog No. ABIN7879273

The Mouse Monoclonal anti-Tyrosinase-Related Protein 1 antibody (Clone TA99-TYRP1-807) (ABIN7879273) specifically detects Tyrosinase-Related Protein 1 in IHC (p). The antibody is reactive with Human samples.

Quick Overview for Tyrosinase-Related Protein 1 antibody (full length) (ABIN7879273)

Target: Tyrosinase-Related Protein 1 (TYRP1)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Tyrosinase-Related Protein 1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TA99-TYRP1-807

Product Details anti-Tyrosinase-Related Protein 1 Antibody

Binding Specificity: full length

Purpose: TRP1 Antibody Cocktail / Tyrosinase-Related Protein-1 / TYRP1

Purification: Protein A/G affinity

Immunogen: SK-MEL-23 cells (clone TA99) and recombinant full-length human TYRP1 protein (clone TYRP1/807) were used as the immunogen for the TRP1 antibody cocktail.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the TRP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the TRP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Tyrosinase-Related Protein 1

Target: Tyrosinase-Related Protein 1 (TYRP1)

Alternative Name: TRP1

Background: It reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.

UniProt: P17643