Recombinant UCHL1 antibody (full length)

Catalog No. ABIN7879276

The Mouse Monoclonal anti-UCHL1 antibody (Clone rUCHL1-4557) (ABIN7879276) specifically detects UCHL1 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for Recombinant UCHL1 antibody (full length) (ABIN7879276)

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This UCHL1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RUCHL1-4557

Product Details anti-UCHL1 Antibody

Binding Specificity: full length

Purpose: Recombinant PGP9.5 Antibody / UchL1

Purification: Protein G affinity chromatography

Immunogen: Recombinant full-length human protein was used as the immunogen for the recombinant PGP9.5 antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the recombinant PGP9.5 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the recombinant PGP9.5 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for UCHL1

Target: UCHL1 (Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))

Alternative Name: PGP9.5

Background: This MAb reacts with a protein of 20-30 kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinsons disease.

UniProt: P09936

Pathways: Feeding Behaviour