ZNF276 antibody (full length)

Catalog No. ABIN7879348

The Mouse Monoclonal anti-ZNF276 antibody (Clone PCRP-ZNF276-1A5) (ABIN7879348) specifically detects ZNF276 in ELISA, IF and FACS. The antibody is reactive with Human samples.

Quick Overview for ZNF276 antibody (full length) (ABIN7879348)

Target: ZNF276 (Zinc Finger Protein 276 (ZNF276))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZNF276 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: PCRP-ZNF276-1A5

Product Details anti-ZNF276 Antibody

Binding Specificity: full length

Purpose: ZNF276 Antibody

Purification: Protein A/G affinity

Immunogen: Recombinant full-length human ZNF276 protein was used as the immunogen for the ZNF276 antibody.

Isotype: IgG2b

Application Details

Application Notes: Optimal dilution of the ZNF276 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ZNF276 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for ZNF276

Target: ZNF276 (Zinc Finger Protein 276 (ZNF276))

Alternative Name: ZNF276

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF276 is a 614 amino acid protein containing five C2H2- type zinc fingers and one zinc finger associated (ZAD) domain. Due to a loss of heterozygosity at the chromosomal location of the gene encoding ZNF276 in sporadic breast cancers, the ZNF276 gene has been targeted as a possible breast cancer tumor suppressor. The FANCA gene, which encodes a DNA repair protein, is situated at the same chromosomal location as the ZNF276 gene, suggesting a possible involvement of ZNF276 in the progression of Fanconi anemia, an autosomal recessive disorder which is caused by mutations in the gene encoding FANCA. There are two isoforms of ZNF276 that exist as a result of an alternative splicing event.

UniProt: Q8N554