NLRP2 antibody (pSer343)

Catalog No. ABIN7879732

The Rabbit Monoclonal anti-NLRP2 antibody (Clone BGI-14) (ABIN7879732) specifically detects NLRP2 in WB. The antibody is reactive with Human samples.

Quick Overview for NLRP2 antibody (pSer343) (ABIN7879732)

Target: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NLRP2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: BGI-14

Product Details anti-NLRP2 Antibody

Binding Specificity: pSer343

Purpose: Phospho-NBS1 Antibody (pS343)

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human NBS1 / NBN (surrounding pS343) was used as the immunogen for the phospho-NBS1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the phospho-NBS1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the phospho-NBS1 antibody at -20oC.

Target Details for NLRP2

Target: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Alternative Name: NBS1

Background: Nijmegen breakage syndrome protein 1 (NBS1) is a component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. [UniProt]

UniProt: O60934

Pathways: Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome