PPP1R12A antibody (pSer668)

Catalog No. ABIN7879764

The Rabbit Polyclonal anti-PPP1R12A antibody is suitable to detect PPP1R12A in samples from Human. It has been validated for WB.

Quick Overview for PPP1R12A antibody (pSer668) (ABIN7879764)

Target: PPP1R12A (Myosin Phosphatase, Target Subunit 1 (PPP1R12A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPP1R12A antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PPP1R12A Antibody

Binding Specificity: pSer668

Purpose: Phospho-MYPT1 Antibody (Ser668)

Predicted Reactivity: Chicken,Mouse,Rat

Purification: Antigen affinity

Immunogen: Amino acids surrounding phosphorylated serine 668 from human MYPT1 were used as the immunogen for the phospho-MYPT1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the phospho-MYPT1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the phospho-MYPT1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PPP1R12A

Target: PPP1R12A (Myosin Phosphatase, Target Subunit 1 (PPP1R12A))

Alternative Name: MYPT1

Background: Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity. [UniProt]

UniProt: O14974

Pathways: M Phase