JAK2 antibody (pTyr1007, pTyr1008)

Catalog No. ABIN7879814

This Rabbit Monoclonal antibody specifically detects JAK2 in WB, ICC and IHC (p). It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for JAK2 antibody (pTyr1007, pTyr1008) (ABIN7879814)

Target: JAK2 (Janus Kinase 2 (JAK2))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This JAK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: IFE-10

Product Details anti-JAK2 Antibody

Binding Specificity: pTyr1007, pTyr1008

Purpose: Phospho-JAK2 Antibody (pY1007/pY1008)

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human JAK2 (surrounding pY1007/pY1008) was used as the immunogen for the phospho-JAK2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the phospho-JAK2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the phospho-JAK2 antibody at -20oC.

Target Details for JAK2

Target: JAK2 (Janus Kinase 2 (JAK2))

Alternative Name: JAK2

Background: Janus kinase 2 is a human protein that has been implicated in signaling by members of the type II cytokine receptor family, the GM-CSF receptor family, the gp130 receptor family, and the single chain receptors.

UniProt: O60674

Pathways: JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response