Recombinant Actin antibody

Catalog No. ABIN7879874

This Rabbit Monoclonal antibody specifically detects Actin in HCP. It exhibits reactivity toward Human.

Quick Overview for Recombinant Actin antibody (ABIN7879874)

Target: Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Actin antibody is un-conjugated

Application: Host Cell Protein Assay (HCP)

Grade: Carrier-free

Clone: ACTA1-9105R

Product Details anti-Actin Antibody

Purpose: Recombinant Alpha Actin 1 Antibody / ACTA1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: Recombinant human ACTA1 protein was used as the immunogen for the recombinant Alpha Actin 1 antibody.

Isotype: IgG, kappa

Application Details

Application Notes: Optimal dilution of the recombinant Alpha Actin 1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the recombinant Alpha Actin 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for Actin

Target: Actin (ACTA1) (Actin, alpha 1, Skeletal Muscle (ACTA1))

Alternative Name: Alpha Actin 1

Background: All eukaryotic cells express Actin, which often constitutes as much as 50 % of total cellular protein. Actin filaments can form both stable and labile structures and are crucial components of microvilli and the contractile apparatus of muscle cells. While lower eukaryotes, such as yeast, have only one Actin gene, higher eukaryotes have several isoforms encoded by a family of genes. At least six types of Actin are present in mammalian tissues and fall into three classes. a-Actin expression is limited to various types of muscle, whereas b and g are the principle constituents of filaments in other tissues. Members of the small GTPase family regulate the organization of the Actin cytoskeleton. Rho controls the assembly of Actin stress fibers and focal adhesion, Rac regulates Actin filament accumulation at the plasma membrane and Cdc42 stimulates formation of filopodia.

UniProt: P68133

Pathways: Caspase Cascade in Apoptosis, Myometrial Relaxation and Contraction, Skeletal Muscle Fiber Development