ABCA4 antibody

Catalog No. ABIN7880018

This Goat Polyclonal antibody specifically detects ABCA4 in ELISA and IF. It exhibits reactivity toward Human and Mouse.

Quick Overview for ABCA4 antibody (ABIN7880018)

Target: ABCA4 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))

Reactivity: Human, Mouse

Host: Goat

Clonality: Polyclonal

Conjugate: This ABCA4 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-ABCA4 Antibody

Purpose: ABCA4 Antibody / ATP-binding cassette sub-family A member 4

Sequence: KQQTESHDLP LHPR

Purification: Antigen affinity

Immunogen: Amino acids KQQTESHDLPLHPR were used as the immunogen for this ABCA4 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Optimal dilution of the ABCA4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in 1X TBS, pH 7.3, with 0.5 % BSA (US sourced) and 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Aliquot and store the ABCA4 antibody at -20oC.

Target Details for ABCA4

Target: ABCA4 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 4 (ABCA4))

Alternative Name: ABCA4

Background: The ABCA4 protein is a transporter molecule responsible for moving retinal molecules across cell membranes in the eye and may have a broader impact on neurological processes. Research has shown that this protein is not restricted to the eyes, but is also present in various regions of the brain. ABCA4 plays a role in the maintenance of lipid homeostasis in the central nervous system. Lipids are essential components of cell membranes and are crucial for neuronal function. Disruptions in lipid metabolism have been implicated in numerous neurological disorders, including Alzheimer's disease and Parkinson's disease. ABCA4 has been found to interact with other proteins involved in synaptic transmission and neuronal signaling. This suggests that the protein may play a role in modulating communication between neurons, which is essential for cognitive function.

UniProt: P16284