Calnexin antibody

Catalog No. ABIN7880142

The Mouse Monoclonal anti-Calnexin antibody is suitable to detect Calnexin in samples from Human. It has been validated for WB, IF, ICC and IHC (p).

Quick Overview for Calnexin antibody (ABIN7880142)

Target: Calnexin (CANX)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Calnexin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: CLNXN-1

Product Details anti-Calnexin Antibody

Purpose: Calnexin Antibody

Purification: Protein G affinity chromatography

Immunogen: A partial human recombinant protein was used as the immunogen for the Calnexin antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: The stated application concentrations are suggested starting points. Titration of the Calnexin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the Calnexin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Target Details for Calnexin

Target: Calnexin (CANX)

Alternative Name: Calnexin

Background: Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins. Associated with partial T-cell antigen receptor complexes that escape the ER of immature thymocytes, it may function as a signaling complex regulating thymocyte maturation. Additionally it may play a role in receptor-mediated endocytosis at the synapse. [UniProt]

UniProt: P27824

Pathways: MAPK Signaling, Thyroid Hormone Synthesis