Recombinant Cathepsin D antibody
Quick Overview for Recombinant Cathepsin D antibody (ABIN7880204)
Target
See all Cathepsin D (CTSD) AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
Grade
Clone
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Purpose
- Recombinant Cathepsin D Antibody / CTSD (azide and preservative free)
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Purification
- Protein A/G affinity
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Immunogen
- A His-tagged CTSD protein was used as the immunogen for the recombinant Cathepsin D antibody.
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Isotype
- IgG, kappa
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Application Notes
- Optimal dilution of the recombinant Cathepsin D antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Preservative
- Azide free
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Storage
- -20 °C
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Storage Comment
- Aliquot the recombinant Cathepsin D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Cathepsin D (CTSD)
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Alternative Name
- Cathepsin D
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Background
- Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 52 kDa preprocathepsin D that is cleaved and glycosylated to form a 48 kDa procathepsin D and then further cleaved to produce 34 kDa and 14 kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.
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UniProt
- P07339
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Pathways
- Peptide Hormone Metabolism
Target
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