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Recombinant Cathepsin D antibody

This Rabbit Monoclonal antibody specifically detects Cathepsin D in IHC (p). It exhibits reactivity toward Human.
Catalog No. ABIN7880204
$640.46
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 2 to 4 Business Days

Quick Overview for Recombinant Cathepsin D antibody (ABIN7880204)

Target

See all Cathepsin D (CTSD) Antibodies
Cathepsin D (CTSD)

Antibody Type

Recombinant Antibody

Reactivity

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Human

Host

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Rabbit

Clonality

  • 95
  • 90
Monoclonal

Conjugate

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This Cathepsin D antibody is un-conjugated

Application

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade

Carrier-free

Clone

CTSD-9613R
  • Purpose

    Recombinant Cathepsin D Antibody / CTSD (azide and preservative free)

    Purification

    Protein A/G affinity

    Immunogen

    A His-tagged CTSD protein was used as the immunogen for the recombinant Cathepsin D antibody.

    Isotype

    IgG, kappa
  • Application Notes

    Optimal dilution of the recombinant Cathepsin D antibody should be determined by the researcher.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    Preservative

    Azide free

    Storage

    -20 °C

    Storage Comment

    Aliquot the recombinant Cathepsin D antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • Target

    Cathepsin D (CTSD)

    Alternative Name

    Cathepsin D

    Background

    Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 52 kDa preprocathepsin D that is cleaved and glycosylated to form a 48 kDa procathepsin D and then further cleaved to produce 34 kDa and 14 kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.

    UniProt

    P07339

    Pathways

    Peptide Hormone Metabolism
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