CD46 antibody

Catalog No. ABIN7880326

The Mouse Monoclonal anti-CD46 antibody (Clone 197-2B1) (ABIN7880326) specifically detects CD46 in FACS and IF. The antibody is reactive with Human samples.

Quick Overview for CD46 antibody (ABIN7880326)

Target: CD46

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD46 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: 197-2B1

Product Details anti-CD46 Antibody

Purpose: CD46 Antibody

Purification: Protein affinity

Immunogen: Recombinant human CD46 protein was used as the immunogen for the CD46 antibody.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal dilution of the CD46 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the CD46 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for CD46

Target: CD46

Alternative Name: CD46

Background: CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria.

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization