Cyclin E2 antibody

Catalog No. ABIN7880527

The Rabbit Monoclonal anti-Cyclin E2 antibody (Clone GHH-3) (ABIN7880527) specifically detects Cyclin E2 in WB. The antibody is reactive with Human samples.

Quick Overview for Cyclin E2 antibody (ABIN7880527)

Target: Cyclin E2 (CCNE2)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Cyclin E2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: GHH-3

Product Details anti-Cyclin E2 Antibody

Purpose: Cyclin E2 Antibody

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Cyclin E2 / CCNE2 was used as the immunogen for the Cyclin E2 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Cyclin E2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the Cyclin E2 antibody at -20oC.

Target Details for Cyclin E2

Target: Cyclin E2 (CCNE2)

Alternative Name: Cyclin E2

Background: G1/S-specific cyclin-E2' belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2. This cyclin has been shown to specifically interact with CIP/KIP family of CDK inhibitors, and plays a role in cell cycle G1/S transition. The expression of this gene peaks at the G1-S phase and exhibits a pattern of tissue specificity distinct from that of cyclin E1. A significantly increased expression level of this gene was observed in tumor-derived cells. [RefSeq]

UniProt: O96020

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases