ELANE antibody

Catalog No. ABIN7880674

The Rabbit Monoclonal anti-ELANE antibody (Clone AOCI-5) (ABIN7880674) specifically detects ELANE in WB. The antibody is reactive with Human samples.

Quick Overview for ELANE antibody (ABIN7880674)

Target: ELANE (Elastase, Neutrophil Expressed (ELANE))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ELANE antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AOCI-5

Product Details anti-ELANE Antibody

Purpose: Neutrophil Elastase Antibody

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Neutrophil Elastase / ELANE was used as the immunogen for the Neutrophil Elastase antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Neutrophil Elastase antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the Neutrophil Elastase antibody at -20oC.

Target Details for ELANE

Target: ELANE (Elastase, Neutrophil Expressed (ELANE))

Alternative Name: Neutrophil Elastase

Background: Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode structurally similar proteins. The encoded preproprotein is proteolytically processed to generate the active protease. Following activation, this protease hydrolyzes proteins within specialized neutrophil lysosomes, called azurophil granules, as well as proteins of the extracellular matrix. The enzyme may play a role in degenerative and inflammatory diseases through proteolysis of collagen-IV and elastin. This protein also degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. [RefSeq]

UniProt: P08246