The Mouse Monoclonal anti-FDPS antibody (Clone 1049CT13-1-4) (ABIN7880764) specifically detects FDPS in WB.
The antibody is reactive with Human and Mouse samples.
The stated application concentrations are suggested starting points. Titration of the FDPS antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Restrictions
For Research Use only
Format
Liquid
Buffer
In 1X PBS, pH 7.4, with 0.09 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot the FDPS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
FDPS
(Farnesyl Diphosphate Synthase (FDPS))
Alternative Name
FDPS
Background
Farnesyl diphosphate synthase is a key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate. [UniProt]