HBEGF antibody

Catalog No. ABIN7881009

The Rabbit Polyclonal anti-HBEGF antibody is suitable to detect HBEGF in samples from Human, Mouse and Rat. It has been validated for WB, FACS, IF and IHC (p).

Quick Overview for HBEGF antibody (ABIN7881009)

Target: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HBEGF antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-HBEGF Antibody

Purpose: HBEGF Antibody / DT-R

Sequence: KKRDPCLRKY KDFCIHGECK YVKE

Purification: Antigen affinity purified

Immunogen: Amino acids KKRDPCLRKYKDFCIHGECKYVKE were used as the immunogen for the HBEGF antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the HBEGF antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the HBEGF antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for HBEGF

Target: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Alternative Name: HBEGF

Background: Heparin-binding EGF-like growth factor (HB-EGF), also called Diphtheria toxin receptor (DT-R), is a member of the EGF family of proteins that in humans is encoded by the HBEGF gene. Enables growth factor activity and heparin binding activity. Involved in several processes, including epidermal growth factor receptor signaling pathway, positive regulation of protein kinase B signaling, and positive regulation of wound healing. Located in cell surface and extracellular space. Implicated in glomerulosclerosis and perinatal necrotizing enterocolitis.

UniProt: Q99075

Pathways: RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway