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HLA-ABC antibody

The Mouse Monoclonal anti-HLA-ABC antibody (Clone SPM419) (ABIN7881085) specifically detects HLA-ABC in FACS and WB. The antibody is reactive with Human samples.
Catalog No. ABIN7881085
$640.46
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 2 to 4 Business Days

Quick Overview for HLA-ABC antibody (ABIN7881085)

Target

See all HLA-ABC Antibodies
HLA-ABC

Reactivity

  • 90
  • 28
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  • 13
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  • 7
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Human

Host

  • 67
  • 18
  • 4
  • 1
Mouse

Clonality

  • 80
  • 9
Monoclonal

Conjugate

  • 44
  • 7
  • 7
  • 7
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
This HLA-ABC antibody is un-conjugated

Application

  • 64
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  • 10
  • 6
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  • 2
  • 1
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Flow Cytometry (FACS), Western Blotting (WB)

Grade

Carrier-free

Clone

SPM419
  • Purpose

    HLA-ABC Antibody (MHC I) (azide and preservative free)

    Purification

    Protein A/G affinity

    Immunogen

    Human peripheral blood leukocytes were used as the immunogen for the HLA-ABC antibody.

    Isotype

    IgG2a, kappa
  • Application Notes

    Optimal dilution of the HLA-ABC antibody should be determined by the researcher.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    1 mg/mL in 1X PBS, BSA free, sodium azide free

    Preservative

    Azide free

    Storage

    -20 °C

    Storage Comment

    Aliquot the HLA-ABC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • Target

    HLA-ABC

    Alternative Name

    HLA-ABC

    Background

    Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

    UniProt

    P01889

    Pathways

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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