HLA-ABC antibody
Quick Overview for HLA-ABC antibody (ABIN7881088)
Target
See all HLA-ABC AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Purpose
- HLA-ABC Antibody
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Purification
- Protein A/G affinity
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Immunogen
- Human REH cells (a pre-B leukaemia cell line) was used as the immunogen for the HLA-ABC antibody.
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Isotype
- IgG2a, kappa
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anti-HLA-ABC (HLA-ABC) antibody
HLA-ABC Reactivity: Human, Cow, Baboon, Cat, Monkey FACS, WB, IHC, IHC (fro), IP Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibody (PE)HLA-ABC Reactivity: Human, Cow, Baboon, Cynomolgus, Rhesus Monkey, Macaque, Shrew, Chimpanzee, Gorilla FACS Host: Mouse Monoclonal W6-32 PE
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC Reactivity: Human, Cow, Baboon, Macaque, Cat, Monkey, Primate, Chimpanzee FACS, IHC (fro), IF, IP, Func, EIA, DNA Mic Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC Reactivity: Human, Cow, Cat, Monkey, Primate FACS, IHC (fro), IF, IP, EIA Host: Mouse Monoclonal W6-32 unconjugated
anti-HLA-ABC (HLA-ABC) antibody (Biotin)HLA-ABC Reactivity: Human, Cow, Baboon, Cynomolgus, Rhesus Monkey, Macaque, Shrew FACS Host: Mouse Monoclonal W6-32 Biotin
anti-HLA-ABC (HLA-ABC) antibody (FITC)HLA-ABC Reactivity: Human, Cow, Baboon, Cynomolgus, Rhesus Monkey, Macaque, Shrew FACS Host: Mouse Monoclonal W6-32 FITC
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC Reactivity: Human FACS, IHC, IHC (fro), IP Host: Rat Monoclonal YTH862-2 unconjugated
anti-HLA-ABC (HLA-ABC) antibodyHLA-ABC Reactivity: Human, Mouse, Non-Human Primate FACS, IF Host: Mouse Monoclonal 246-B8-E7 unconjugated
anti-HLA-ABC (HLA-ABC) antibody (PE)GMP Grade HLA-ABC Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey FACS Host: Mouse Monoclonal W6-32 PE
anti-HLA-ABC (HLA-ABC) antibody (FITC)GMP Grade HLA-ABC Reactivity: Human, Baboon, Cynomolgus, Rhesus Monkey FACS Host: Mouse Monoclonal W6-32 FITC
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Application Notes
- Optimal dilution of the HLA-ABC antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- Aliquot the HLA-ABC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- HLA-ABC
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Alternative Name
- HLA-ABC
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Background
- Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Immunoprecipitation of lactoperoxidase radioiodinated cell surface proteins and surface sialoglycoproteins radiolabeled by sodium metaperiodate/tritiated sodium borohydride technique confirmed the structure gp44,p12 (consisting of a 44 kDa glycopeptide linked with a non-glycosylated 12 kDa peptide) typical for MHC class I antigen(s) as a structure recognized by Bra23/9. Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
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UniProt
- P01889
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Pathways
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Target
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