ITGA4 antibody

Catalog No. ABIN7881188

This Rabbit Monoclonal antibody specifically detects ITGA4 in WB. It exhibits reactivity toward Human.

Quick Overview for ITGA4 antibody (ABIN7881188)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This ITGA4 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: IHH-9

Product Details anti-ITGA4 Antibody

Purpose: ITGA4 Antibody / Integrin alpha 4

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Integrin alpha 4 / ITGA4 was used as the immunogen for the ITGA4 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the ITGA4 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the ITGA4 antibody at -20oC.

Target Details for ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Alternative Name: ITGA4

Background: The ITGA4 gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn's disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [RefSeq]

UniProt: P13612

Pathways: Integrin Complex