Integrin Alpha2b antibody

Catalog No. ABIN7881195

The Rabbit Monoclonal anti-Integrin Alpha2b antibody is suitable to detect Integrin Alpha2b in samples from Human. It has been validated for WB.

Quick Overview for Integrin Alpha2b antibody (ABIN7881195)

Target: Integrin Alpha2b (CD41)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AAGH-9

Product Details anti-Integrin Alpha2b Antibody

Purpose: CD41 Antibody / ITGA2B

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human CD41 / ITGA2B was used as the immunogen for the CD41 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the CD41 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the CD41 antibody at -20oC.

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: CD41

Background: The ITGA2B gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [RefSeq]

UniProt: P08514

Pathways: Integrin Complex