IRF1 antibody

Catalog No. ABIN7881245

This Rabbit Monoclonal antibody specifically detects IRF1 in WB and IHC (p). It exhibits reactivity toward Human and Rat.

Quick Overview for IRF1 antibody (ABIN7881245)

Target: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IRF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: DHE-9

Product Details anti-IRF1 Antibody

Purpose: IRF1 Antibody / Interferon regulatory factor 1

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human Interferon regulatory factor 1 was used as the immunogen for the IRF1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the IRF1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the IRF1 antibody at -20oC.

Target Details for IRF1

Target: IRF1 (Interferon Regulatory Factor 1 (IRF1))

Alternative Name: IRF1

Background: The protein encoded by the IRF1 gene is a transcriptional regulator and tumor suppressor, serving as an activator of genes involved in both innate and acquired immune responses. The encoded protein activates the transcription of genes involved in the body's response to viruses and bacteria, playing a role in cell proliferation, apoptosis, the immune response, and DNA damage response. This protein represses the transcription of several other genes. As a tumor suppressor, it both suppresses tumor cell growth and stimulates an immune response against tumor cells. Defects in this gene have been associated with gastric cancer, myelogenous leukemia, and lung cancer. [RefSeq]

UniProt: P10914

Pathways: Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Immune Effector Process, Hepatitis C, Autophagy