Recombinant KRT6A antibody

Catalog No. ABIN7881409

The Rabbit Monoclonal anti-KRT6A antibody is suitable to detect KRT6A in samples from Human. It has been validated for IHC (p).

Quick Overview for Recombinant KRT6A antibody (ABIN7881409)

Target: KRT6A (Keratin 6A (KRT6A))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This KRT6A antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: KRT6-3997R

Product Details anti-KRT6A Antibody

Purpose: Keratin 6A Antibody / Cytokeratin 6A (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant protein fragment was used as the immunogen for the Cytokeratin 6A antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the Cytokeratin 6A antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the Cytokeratin 6A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for KRT6A

Target: KRT6A (Keratin 6A (KRT6A))

Alternative Name: Keratin 6A

Background: Cytokeratin 6 is an epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. This protein always paired with the type-I keratin K16. Cytokeratin 6 have been identified in epidermis only in samples from plantar glabrous skin while in hairy skin this keratin appeared to be absent in interfollicular epidermis but were clearly present in hair follicle outer root sheath, and this protein also consistently expressed in non-keratinizing stratified squamous epithelia. Among tumors, cytokeratin 6 is typically and strongly expressed in squamous cell carcinomas of different sites, preferentially in inner, maturing layers of the tumor cell nests. Cytokeratin 6 is always used with cytokeratin 5 and is a useful aid for classification of epithelioid mesotheliomas.

UniProt: P02538