LEF1 antibody

Catalog No. ABIN7881493

The Mouse Monoclonal anti-LEF1 antibody is suitable to detect LEF1 in samples from Human. It has been validated for IHC (p).

Quick Overview for LEF1 antibody (ABIN7881493)

Target: LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This LEF1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: Carrier-free

Clone: LEF1-6764

Product Details anti-LEF1 Antibody

Purpose: TCF1 alpha Antibody / T cell specific transcription factor 1 alpha / LEF1 (azide and preservative free)

Purification: Protein A/G affinity

Immunogen: A recombinant fragment of human LEF1 protein was used as the immunogen for the TCF1 alpha antibody.

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal dilution of the TCF1 alpha antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Preservative: Azide free

Storage: -20 °C

Storage Comment: Aliquot the TCF1 alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for LEF1

Target: LEF1 (Lymphoid Enhancer-Binding Factor 1 (LEF1))

Alternative Name: TCF1 alpha

Background: Lymphoid Enhancing Factor 1 (LEF1), also called TCF1 alpha, is a transcription factor that belongs to the TCF/LEF family. LEF1 participates as a regulator in Wnt signaling pathways. LEF1 is an important factor in lymphopoiesis and is expressed normally in T and pro-B cells but not expressed in mature B cells. Anti-LEF1 may be used as an aid for differentiation of chronic lymphocytic leukemia/small lymphocytic lymphoma from other small B cell lymphomas.

UniProt: Q9UJU2

Pathways: WNT Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Hormone Metabolic Process, Nuclear Hormone Receptor Binding, Chromatin Binding