MMP2 antibody

Catalog No. ABIN7881559

The Mouse Monoclonal anti-MMP2 antibody is suitable to detect MMP2 in samples from Human. It has been validated for IHC (p).

Quick Overview for MMP2 antibody (ABIN7881559)

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MMP2 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: MMP2-4586

Product Details anti-MMP2 Antibody

Purpose: Matrix metalloproteinase 2 Antibody / MMP2

Purification: Protein A/G affinity

Immunogen: Recombinant human protein was used as the immunogen for the Matrix metalloproteinase 2 antibody.

Isotype: IgG2b, kappa

Application Details

Application Notes: Optimal dilution of the Matrix metalloproteinase 2 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the Matrix metalloproteinase 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for MMP2

Target: MMP2 (Matrix Metalloproteinase 2 (MMP2))

Alternative Name: Matrix metalloproteinase 2

Background: It recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway.

UniProt: P08253

Pathways: Activation of Innate immune Response