MBD3 antibody

Catalog No. ABIN7881628

The Rabbit Monoclonal anti-MBD3 antibody is suitable to detect MBD3 in samples from Human. It has been validated for WB.

Quick Overview for MBD3 antibody (ABIN7881628)

Target: MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This MBD3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: AFEE-13

Product Details anti-MBD3 Antibody

Purpose: MBD3 Antibody

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human MBD3 was used as the immunogen for the MBD3 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the MBD3 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the MBD3 antibody at -20oC.

Target Details for MBD3

Target: MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

Alternative Name: MBD3

Background: DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. The MBD3 gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. [RefSeq]

UniProt: O95983

Pathways: Chromatin Binding