NLRP2 antibody

Catalog No. ABIN7881816

This Rabbit Monoclonal antibody specifically detects NLRP2 in WB and IHC (p). It exhibits reactivity toward Human and Rat.

Quick Overview for NLRP2 antibody (ABIN7881816)

Target: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NLRP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: COF-14

Product Details anti-NLRP2 Antibody

Purpose: NBS1 Antibody / NBN

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human NBS1 / NBN was used as the immunogen for the NBS1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the NBS1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the NBS1 antibody at -20oC.

Target Details for NLRP2

Target: NLRP2 (NLR Family, Pyrin Domain Containing 2 (NLRP2))

Alternative Name: NBS1

Background: Nijmegen breakage syndrome protein 1 (NBS1) is a component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double-strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. [UniProt]

UniProt: O60934

Pathways: Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome