The Rabbit Monoclonal anti-OGT antibody (Clone AEDG-15) (ABIN7881869) specifically detects OGT in WB.
The antibody is reactive with Human, Mouse and Rat samples.
The OGT encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. [RefSeq]