PIM1 antibody

Catalog No. ABIN7881952

The Rabbit Monoclonal anti-PIM1 antibody is suitable to detect PIM1 in samples from Human and Mouse. It has been validated for WB and IHC (p).

Quick Overview for PIM1 antibody (ABIN7881952)

Target: PIM1 (Pim-1 Oncogene (PIM1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PIM1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: ECB-16

Product Details anti-PIM1 Antibody

Purpose: PIM1 Antibody

Purification: Affinity purified

Immunogen: A synthetic peptide specific to human PIM1 was used as the immunogen for the PIM1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the PIM1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store the PIM1 antibody at -20oC.

Target Details for PIM1

Target: PIM1 (Pim-1 Oncogene (PIM1))

Alternative Name: PIM1

Background: The protein encoded by the PIM1 gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons. [RefSeq]

UniProt: P11309

Pathways: Glycosaminoglycan Metabolic Process