KCNJ1 antibody

Catalog No. ABIN7882004

The Rabbit Polyclonal anti-KCNJ1 antibody (ABIN7882004) specifically detects KCNJ1 in WB. The antibody is reactive with Rat, Mouse and Monkey samples.

Quick Overview for KCNJ1 antibody (ABIN7882004)

Target: KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))

Reactivity: Rat, Mouse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNJ1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-KCNJ1 Antibody

Purpose: KCNJ1 Antibody

Sequence: WYAVAYIHKD LPEFH

Purification: Affinity purified

Immunogen: Amino acids WYAVAYIHKDLPEFH from the human protein were used as the immunogen for the KCNJ1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the KCNJ1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: 4 °C,-20 °C

Storage Comment: After reconstitution, the KCNJ1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Target Details for KCNJ1

Target: KCNJ1 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 1 (KCNJ1))

Alternative Name: KCNJ1

Background: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: P48048