Recombinant P4HTM antibody

Catalog No. ABIN7882047

This Rabbit Monoclonal antibody specifically detects P4HTM in WB. It exhibits reactivity toward Human.

Quick Overview for Recombinant P4HTM antibody (ABIN7882047)

Target: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This P4HTM antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 28P22

Product Details anti-P4HTM Antibody

Purpose: P4HTM Antibody / HIF Prolyl Hydroxylases / HIFPH4

Purification: Affinity chromatography

Immunogen: A synthetic peptide derived from human HIF Prolyl Hydroxylases was used as the immunogen for the P4HTM antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the P4HTM antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Antibody in PBS with 0.02 % sodium azide, 50 % glycerol and 0.4-0.5 mg/mL BSA

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store the P4HTM antibody at -20oC.

Target Details for P4HTM

Target: P4HTM (Prolyl 4-Hydroxylase, Transmembrane (Endoplasmic Reticulum) (P4HTM))

Alternative Name: P4HTM

Background: Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF1A at 'Pro-402' and 'Pro-564'. May function as a cellular oxygen sensor and, under normoxic conditions, may target HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. [UniProt]

UniProt: Q9NXG6