Prostate Specific Antigen antibody
Quick Overview for Prostate Specific Antigen antibody (ABIN7882061)
Target
See all Prostate Specific Antigen (PSA) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
Clone
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Purpose
- PSA Antibody / Prostate Specific Antigen (azide and preservative free)
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Purification
- Protein G affinity chromatography
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Immunogen
- Human Prostate Specific Antigen was used as the immunogen for the PSA antibody.
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Isotype
- IgG1, kappa
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Application Notes
- Optimal dilution of the PSA antibody should be determined by the researcher.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Preservative
- Azide free
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store the PSA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
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- Prostate Specific Antigen (PSA)
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Alternative Name
- PSA
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Background
- Recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb A67-B/E3 for PSA tests.
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UniProt
- P07288
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Pathways
- Complement System
Target
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